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    首頁(yè) > 產(chǎn)品中心 > 生化試劑 > 小分子化合物 > abs47027083Octopamine hydrochloride 770-05-8

    Octopamine hydrochloride 770-05-8

    簡(jiǎn)要描述:Octopamine hydrochloride 770-05-8
    儲(chǔ)存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

    • 產(chǎn)品型號(hào):abs47027083
    • 廠商性質(zhì):生產(chǎn)廠家
    • 更新時(shí)間:2025-11-25
    • 訪  問(wèn)  量:996

    詳細(xì)介紹

    品牌absinCAS770-05-8
    分子式C8H12CINO2純度99%
    分子量189.64貨號(hào)abs47027083
    規(guī)格500mg供貨周期現(xiàn)貨
    主要用途acts as a neurohormone應(yīng)用領(lǐng)域化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

    Octopamine hydrochloride  770-05-8

    產(chǎn)品描述
    描述

    Octopamine (OA), a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates.

    純度
    99%
    儲(chǔ)存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    基本信息
    別名
    章胺鹽酸鹽; (+,-)-Octopamine HCl;(±)-p-Octopamine hydrochlorid
    外觀
    white or off-white solid
    可溶性/溶解性
    DMSO : ≥ 100 mg/mL (527.31 mM)
    water : ≥ 50 mg/mL (263.66 mM)
    生物活性
    In vitro(體外研究)
    Octopamine is present in relatively high concentrations in neuronal as well as in non-neuronal tissues of most invertebrate species studied, and modulates almost every physiological process. Octopamine acts as neurohormone including desensitization of sensory inputs, influence on learning and memory, or regulation of the mood of the animal in the central nervous system. Octopamine is the only neuroactive non-peptide transmitter whose physiological role is restricted to invertebrates, and all octopamine receptors belong to the family of G-protein coupled receptors.
    In vivo(體內(nèi)研究)
    Octopamine (10 mg/mL) is necessary for the acquisition of sugar memory in Drosophila. Octopamine treatment increases responsiveness to brood pheromone and decreased responsiveness to social inhibition. Octopamine acts as an important source of variation in response thresholds and as a modulator of pheromonal communication in insect societies. Octopamine (10 μM) injected into the mushroom body (MB) calyces or the antennal lobe but not the lateral protocerebral lobe produces a lasting, pairing-specific enhancement of extension of the proboscis. Octopamine (10 μM) injected into the MB calyces results in an additional pairing-specific effect, because it does not lead to an acquisition but a consolidation after conditioning. Octopamine treatment significantly elevates levels of octopamine in the brain and caused a significant dose-dependent increase in the number of new foragers. Octopamine treatment is effective only when given to bees old enough to forage, i.e., older than 4 days of age. Octopamine influences division of labor in honey bee colonies.
    參考文獻(xiàn)
    參考文獻(xiàn)
    研究領(lǐng)域
    研究領(lǐng)域
    Neuroscience
    NeuroscienceEndocrine system
    Drug DiscoverySmall Molecule DrugLead Compound Discovery
    Octopamine hydrochloride  770-05-8溫馨提示:本產(chǎn)品僅作科研實(shí)驗(yàn)使用,不支持臨床等研究

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