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    Tryptamine 61-54-1

    簡要描述:Tryptamine 61-54-1
    Tryptamine is a monoamine alkaloid found in plants, fungi, and animals.

    • 產(chǎn)品型號:abs47027221
    • 廠商性質(zhì):生產(chǎn)廠家
    • 更新時間:2025-12-02
    • 訪  問  量:718

    詳細(xì)介紹

    品牌absinCAS61-54-1
    分子式C10H12N2純度>98%
    分子量160.22貨號abs47027221
    規(guī)格25mg供貨周期現(xiàn)貨
    主要用途is a monoamine alkaloid應(yīng)用領(lǐng)域化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

    Tryptamine 61-54-1

    產(chǎn)品描述
    描述

    Tryptamine is a monoamine alkaloid found in plants, fungi, and animals. It contains an indole ring structure, and is structurally similar to the amino acid tryptophan, from which it derives its name. Tryptamine is found in trace amounts in the brains of mammals and is believed to play a role as a neuromodulator or neurotransmitter.

    純度
    >98%
    儲存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    基本信息
    別名
    色胺
    外觀
    類白色粉末
    可溶性/溶解性
    DMSO : ≥ 150 mg/mL (936.21 mM)
    生物活性
    靶點(diǎn)
    hTAAR1
    In vitro(體外研究)
    High concentrations of tryptamine (0.1-1 mM) induce autophagy in HT22 and SK-N-SH nerve cell lines and in primary cultures of astrocytes, glial cells being less sensitive than neurons.
    In vivo(體內(nèi)研究)
    Tryptamine at a dose of 50 mg/kg i.p. induces an inhibition of locomotor activity and, at doses ranging from 150 to 300 mg/kg, induces peculiar behaviors such as head twitch, head weaving, forepaw treading, hindlimb abduction and Straub tail. Tryptamine induces both the depression and excitation in the behavior of mice depending on the dosage and Tryptamine-induced excitatory behaviors may be attributed to both its direct stimulation of 5-HT receptors and facilitation of 5-HT release.
    參考文獻(xiàn)
    參考文獻(xiàn)
    • 1. Berman HM, et al. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.

    • 2. Zhang Z, et al. Biosens Bioelectron. 2014 Oct 15;60:161-6.

    • 3. Paley EL, et al. Curr Alzheimer Res. 2013 Nov;10(9):987-1004.

    研究領(lǐng)域
    研究領(lǐng)域
    Drug DiscoverySmall Molecule DrugLead Compound Discovery
    Tryptamine 61-54-1溫馨提示:本產(chǎn)品僅作科研實(shí)驗(yàn)使用,不支持臨床等研究

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