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    首頁 > 產(chǎn)品中心 > 生化試劑 > 小分子化合物 > abs47027327Cianidanol 154-23-4

    Cianidanol 154-23-4

    簡要描述:Cianidanol 154-23-4
    Catechin((+)-Catechin; D-Catechin) is a flavan-3-ol, a type of natural phenol and antioxidant.

    • 產(chǎn)品型號:abs47027327
    • 廠商性質(zhì):生產(chǎn)廠家
    • 更新時間:2025-12-08
    • 訪  問  量:758

    詳細(xì)介紹

    品牌absinCAS154-23-4
    分子式C15H14O6純度>98%
    分子量290.27貨號abs47027327
    規(guī)格10mg供貨周期現(xiàn)貨
    主要用途is a flavan-3-ol,應(yīng)用領(lǐng)域化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

    Cianidanol 154-23-4

    產(chǎn)品描述
    描述

    Catechin((+)-Catechin; D-Catechin) is a flavan-3-ol, a type of natural phenol and antioxidant.

    純度
    >98%
    儲存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    基本信息
    可溶性/溶解性
    DMSO
    58mg/ml(199.81 mM)
    Water
    58mg/ml(199.81 mM)
    生物活性
    靶點(diǎn)
    COX-1 ,COX-2
    In vitro(體外研究)
    The catechin flavonoid reduces proliferation and induces apoptosis of murine lymphoma cells LB02 through modulation of antiapoptotic proteins. Treatment of human prostate cancer cells with catechin induces apoptosis and results in effects on a variety of survival signals suggesting the potential of these compounds as chemopreventive agents for prostate cancer. Catechin is well known to inhibit cyclooxygenase activity with reported IC50 values ranging from 4O μM to 943 μM. It has also been reported to act as an inhibitor of COX-1 and COX-2 with IC50 of about 80 µM and 130 μM.
    In vivo(體內(nèi)研究)
    Dietary catechin significantly delayed tumor onset. Continued intake of catechin, a potential antioxidant, prevents memory regression and DNA oxidative damage in senescence-accelerated (SAMP10) mice. It does not prolong the lifetime of SAMP10 mice, but it does delay brain senescence. (+)-Catechin inhibits intestinal tumor formation and suppresses Focal adhesion kinase activation in the Min/+ Mouse.
    參考文獻(xiàn)
    參考文獻(xiàn)
    • 1. Bhujbal NN, et al. Carbohydr Res. 2009 Apr 21;344(6):734-8.

    • 2. Zhang Q, et al. Inflamm Res. 2014 Aug;63(8):619-28.

    研究領(lǐng)域
    研究領(lǐng)域
    CancerTumor immunology
    Drug DiscoverySmall Molecule DrugLead Compound Discovery

    Cianidanol 154-23-4

    溫馨提示:本產(chǎn)品僅作科研實驗使用,不支持臨床等研究

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