Fenofibrate 49562-28-9

簡(jiǎn)要描述：Fenofibrate 49562-28-9
Fenofibrate is a Peroxisome Proliferator Receptor alpha Agonist.

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品牌	absin	CAS	49562-28-9
分子式	C20H21ClO4	純度	98%
分子量	360.83	貨號(hào)	abs47027522
規(guī)格	100mg	供貨周期	現(xiàn)貨
主要用途	is a Peroxisome Proliferator Receptor al	應(yīng)用領(lǐng)域	化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

Fenofibrate 49562-28-9

產(chǎn)品描述
描述	Fenofibrate is a Peroxisome Proliferator Receptor alpha Agonist. The mechanism of action of fenofibrate is as a Peroxisome Proliferator-activated Receptor alpha Agonist. The chemical classification of fenofibrate is PPAR alpha.
純度	98%
儲(chǔ)存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
基本信息
別名	fei諾貝特
外觀	白色或類白色結(jié)晶性粉末
可溶性/溶解性	DMSO : 36.1 mg/mL (100 mM) Ethanol : 36.1 mg/mL (100 mM)
生物活性
靶點(diǎn)	Cytochrome P450
In vivo(體內(nèi)研究)	Daily intake of Fenofibrate at this low dose (10 μg/g/day) inhibits retinal and choroidal neovascularization induced by CYP2C8 overexpression by 29% (P=0.021) and 36% (P=1.2×10?9) respectively.
參考文獻(xiàn)
參考文獻(xiàn)	1. Clavey V, et al. Cell Physiol Biochem. 1999;9(3):139-49. 2. Walsky RL, et al. J Clin Pharmacol. 2005 Jan;45(1):68-78. 3. Casas F, et al. FEBS Lett. 2000 Sep 29;482(1-2):71-4. 4. Bouly M, et al. J Biol Chem. 2001 Jul 13;276(28):25841-7.

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CardiovascularLipids / LipoproteinsLipid MetabolismCytochromes

MetabolismPathways and ProcessesMetabolic signaling pathwaysDrug metabolism

MetabolismPathways and ProcessesMetabolic signaling pathwaysLipid and lipoprotein metabolismLipases

MetabolismPathways and ProcessesMitochondrial MetabolismCytochromes

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Signal TransductionMetabolismDrug metabolism

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