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簡要描述：Nadifloxacin 124858-35-1Nadifloxacin(OPC7251) is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris.
產(chǎn)品型號：abs47027710廠商性質(zhì)：生產(chǎn)廠家更新時間：2025-12-25訪 問 量：583產(chǎn)品分類
Product Category詳細(xì)介紹
| 品牌 | absin | CAS | 124858-35-1 |
|---|---|---|---|
| 分子式 | C19H21FN2O4 | 純度 | 99% |
| 分子量 | 360.39 | 貨號 | abs47027710 |
| 規(guī)格 | 25mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | is a topical fluoroquinolone antibiotic | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Nadifloxacin 124858-35-1
| 產(chǎn)品描述 | |
| 描述 | Nadifloxacin(OPC7251) is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris. |
| 純度 | 99% |
| 儲存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 那氟sha星；OPC7251 |
| 外觀 | 灰白色結(jié)晶固體 |
| 可溶性/溶解性 | DMSO : 16 mg/mL (44.4 mM) |
| 生物活性 | |
| In vitro(體外研究) | Nadifloxacin is a potent, broad-spectrum, quinolone agent approved for topical use in acne vulgaris and skin infections. Nadifloxacin inhibits the enzyme DNA gyrase that is involved in bacterial DNA synthesis and replication, thus inhibiting the bacterial multiplication. In vitro studies of nadifloxacin show potent and broad-spectrum antibacterial activity against aerobic Gram-positive, Gram-negative and anaerobic bacteria. Additionally, studies also suggest that the effectiveness of nadifloxacin in inflammatory acne lesions may be attributed to its inhibitory effect on pro-inflammatory cytokines like interleukin (IL)-1α, IL-6, and IL-8 which also play an important role in acne pathogenesis. |
| 參考文獻(xiàn) | |
| 參考文獻(xiàn) |
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| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | MetabolismTypes of disease Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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