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    Levamlodipine 103129-82-4

    簡要描述:Levamlodipine 103129-82-4
    Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.

    • 產(chǎn)品型號:abs47027751
    • 廠商性質(zhì):生產(chǎn)廠家
    • 更新時間:2025-12-29
    • 訪  問  量:662

    詳細介紹

    品牌absinCAS103129-82-4
    分子式C20H25N2O5Cl純度98%
    分子量408.88貨號abs47027751
    規(guī)格5mg供貨周期現(xiàn)貨
    主要用途is a synthetic dihydropyridine應用領域化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

    Levamlodipine 103129-82-4

    產(chǎn)品描述
    描述
    Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug response (MDR) activity through inhibition of the p-glycoprotein efflux pump.
    純度
    98%
    儲存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    基本信息
    可溶性/溶解性
    10 mM in DMSO
    生物活性
    靶點
    calcium channel
    In vitro(體外研究)
    Amlodipine is a calcium channel blocker prescribed for the management of angina and hypertension. As a racemic mixture, amlodipine contains (R)- and (S)-amlodipine isomers, but only (S)-amlodipine as the active moiety possesses therapeutic activity.
    參考文獻
    參考文獻
    • 1. Gui H, et al. CNS Neurosci Ther. 2013 Mar;19(3):178-82.

    • 2. Qi Y, Zhang X. Cell Biochem Biophys. 2014 Dec;70(3):1633-7.

    研究領域
    研究領域
    Drug DiscoverySmall Molecule DrugLead Compound Discovery
    Levamlodipine 103129-82-4溫馨提示:本產(chǎn)品僅作科研實驗使用,不支持臨床等研究

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