Wiskostatin 253449-04-6

簡要描述：Wiskostatin 253449-04-6
Wiskott-Aldrich syndrome protein (WASP) and WAVE stimulate actin-related protein (Arp)2/3-mediated actin polymerization

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品牌	absin	CAS	253449-04-6
分子式	C17H18Br2N2O	純度	98%
分子量	426.15	貨號	abs47027924
規(guī)格	1mg	供貨周期	現(xiàn)貨
主要用途	is a recently described chemical inhibit	應(yīng)用領(lǐng)域	化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合

Wiskostatin 253449-04-6

產(chǎn)品描述
描述	Wiskott-Aldrich syndrome protein (WASP) and WAVE stimulate actin-related protein (Arp)2/3-mediated actin polymerization, leading to diverse downstream effects, including the formation and remodeling of cell surface protrusions, modulation of cell migration, and intracytoplasmic propulsion of organelles and pathogens. Selective inhibitors of individual Arp2/3 activators would enable more exact dissection of WASP- and WAVE-dependent cellular pathways and are potential therapeutic targets for viral pathogenesis. Wiskostatin is a recently described chemical inhibitor that selectively inhibits neuronal WASP (N-WASP)-mediated actin polymerization in vitro.
純度	98%
儲存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
基本信息
別名	1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol
外觀	white to beige powder
可溶性/溶解性	10 mM in DMSO
參考文獻(xiàn)
參考文獻(xiàn)	1. Guerriero CJ, Weisz OA. Am J Physiol Cell Physiol. 2007 Apr;292(4):C1562-6. 2. Bompard G, et al. BMC Cell Biol. 2008 Jul 30;9:42.

研究領(lǐng)域
研究領(lǐng)域	Neuroscience Drug DiscoverySmall Molecule DrugLead Compound Discovery

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