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18438616290
簡(jiǎn)要描述：Diaveridine 5355-16-8Diaveridine (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide. It has been reported to be genotoxic to mammalian cells
產(chǎn)品型號(hào)：abs47027944廠商性質(zhì)：生產(chǎn)廠家更新時(shí)間：2026-01-08訪 問 量：587產(chǎn)品分類
Product Category詳細(xì)介紹
| 品牌 | absin | CAS | 5355-16-8 |
|---|---|---|---|
| 分子式 | C13H16N4O2 | 純度 | 99% |
| 分子量 | 260.29 | 貨號(hào) | abs47027944 |
| 規(guī)格 | 5mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | used in combination with sulfonamide | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Diaveridine 5355-16-8
| 產(chǎn)品描述 | |
| 描述 | Diaveridine (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide. It has been reported to be genotoxic to mammalian cells, but more studies are required to clarify this.[1] |
| 純度 | 99% |
| 儲(chǔ)存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 敵菌凈；二氨藜蘆啶；EGIS-5645 |
| 外觀 | 白色或淡黃色結(jié)晶性粉末 |
| 可溶性/溶解性 | DMSO : 32 mg/mL (122.94 mM; Need ultrasonic) |
| 生物活性 | |
| 靶點(diǎn) | DHFR |
| In vitro(體外研究) | Diaveridine (DVD) is a pyrimethamine analogue, a folic acid antagonist. It is also used as an antibacterial agent, especially for the respiratory and gastrointestinal tract infections in humans and animals. Diaveridine is genotoxic in mammalian cells in vitro and in vivo. |
| In vivo(體內(nèi)研究) | Acute tests indicate that the diaveridine has a high LD50 value and suggests a wide margin of safety for therapeutic doses. |
| 參考文獻(xiàn) | |
| 參考文獻(xiàn) |
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| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | Signal TransductionMetabolism Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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