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簡(jiǎn)要描述：Terconazole 67915-31-5Arecoline is a muscarinic acetylcholine receptor agonist. Arecoline induces ADP ribosylation of histones and chromatid relaxation in spleen and bone marrow cells.
產(chǎn)品型號(hào)：abs47027950廠商性質(zhì)：生產(chǎn)廠家更新時(shí)間：2026-01-08訪 問(wèn) 量：667產(chǎn)品分類
Product Category詳細(xì)介紹
| 品牌 | absin | CAS | 67915-31-5 |
|---|---|---|---|
| 分子式 | C26H31Cl2N5O3 | 純度 | ≥98% |
| 分子量 | 532.46 | 貨號(hào) | abs47027950 |
| 規(guī)格 | 50mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | is a muscarinic acetylcholine receptor a | 應(yīng)用領(lǐng)域 | 化工,生物產(chǎn)業(yè),農(nóng)林牧漁,制藥/生物制藥,綜合 |
Terconazole 67915-31-5
| 產(chǎn)品描述 | |
| 描述 | Arecoline is a muscarinic acetylcholine receptor agonist. Arecoline induces ADP ribosylation of histones and chromatid relaxation in spleen and bone marrow cells. |
| 純度 | ≥98% |
| 儲(chǔ)存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 特康唑；曲康唑；R42470 |
| 外觀 | white powder |
| 可溶性/溶解性 | DMSO : ≥ 30 mg/mL (56.34 mM) |
| 生物活性 | |
| In vitro(體外研究) | Terconazole inhibits the growth of Candida albicans ATCC 44859 in a concentration-related manner, but with modest effects noted at levels from 0.1 to 10 μM when the yeast is grown on media favoring the cell form. The inhibitory potency of terconazole on yeast cell viability varies with the strain and species of Candida tested. The susceptibility of C. albicans ATCC 44859 to terconazole is markedly enhanced when the yeast is grown on Eagle minimum essential medium, which favors mycelium formation. There is a progression of changes, from loss of mycelia formation at 0.1 μM terconazole through complete necrosis at 100 μM. Terconazole blocks the morphogenetic transformation from the yeast into the filamentous form at concentrations of 0.008 to 0.05 microgram/mL. |
| In vivo(體內(nèi)研究) | A 3-day once-daily intravaginal application of terconazole 0.8% is usually sufficient to provide a functional therapeutic period of 7 days because of prolonged high biologically active antifungal levels in the vagina. No side effects are observed at any concentration of terconazole. |
| 參考文獻(xiàn) | |
| 參考文獻(xiàn) |
| 研究領(lǐng)域 | |
| 研究領(lǐng)域 | MetabolismTypes of disease Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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