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簡要描述：Acotiamide hydrochloride hydrate 773092-05-0Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity.
產品型號：abs47027993廠商性質：生產廠家更新時間：2026-01-12訪 問 量：578產品分類
Product Category詳細介紹
| 品牌 | absin | CAS | 773092-05-0 |
|---|---|---|---|
| 分子式 | C21H37ClN4O8S | 純度 | 98% |
| 分子量 | 541.06 | 貨號 | abs47027993 |
| 規(guī)格 | 10mg | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | is the hydrochloride salt form of acotia | 應用領域 | 化工,生物產業(yè),農林牧漁,制藥/生物制藥,綜合 |
Acotiamide hydrochloride hydrate 773092-05-0
| 產品描述 | |
| 描述 | Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamide exerts its effect has yet to be fully elucidated, this agent appears to inhibit acetylcholinesterase (AchE), an enzyme responsible for the breakdown of acetylcholine (Ach). Increased Ach concentrations lead to an improvement of gastric emptying and GI motility and eventually to a reduction of dyspepsia symptoms. |
| 純度 | 98% |
| 儲存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 別名 | 鹽酸阿考替胺三水合物 |
| 可溶性/溶解性 | 10 mM in DMSO |
| 生物活性 | |
| In vitro(體外研究) | Acotiamide inhibits AChE with half maximal inhibitory concentrations (IC50) of 3.0, 2.3 and 1.2 μM for human recombinant, and rat and canine gastric AChEs, respectively. |
| In vivo(體內研究) | Acotiamide is concentrated into the stomach tissue by carrier-mediated uptake processes, which may account for the selective action of acotiamide for gastric smooth muscle but not for skeletal muscle and central nervous system in rats. |
| 參考文獻 | |
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| 研究領域 | |
| 研究領域 | Immunology Metabolism Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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